+420 602 554 176
Opava, Czech Republic

Welcome to Mihulka

Synthesis of small molecules for the pharmaceutical industry

Including cGMP synthesis of active pharmaceutical ingredients (APIs), intermediates and raw materials.


Explore Our Main Services

Mihulka offers a full-service custom synthesis development, process scale-up, and technology transfer from laboratory to pilot and commercial production scales.
About Us

About Us

Our Goals and Visions

We strive to be recognized as a preferred contract manufacturing organization (CMO) specializing in the development of value-added novel and innovative syntheses.

Our Team

Meet our Specialists

We have a highly dedicated and experienced staff. Every member of our team has a technical degree and significant professional history.

Don’t hesitate, contact us for better help. Explore all Specialists.


Environmental Awareness and Certificates

The company emphasizes environmentally conscious approach for all of its activities. The aim is to develop efficient synthetic routes with minimum waste using environmentally friendly procedures, including the implementation of high yield synthetic steps and cryo-condensation of solvent vapours for efficient solvent recoveries. Any residual waste is discarded at a dedicated disposal facility. In addition, Mihulka operates its own biological wastewater treatment plant.

The company has the following certificates


GMP certificates by State Institute for Drug Control, Czech Republic (SÚKL)


Permit issued by the Czech Ministry of Health for handling of psychotropic precursors (ergotamin, ergometrin, lysergic acid)

Mihulka s.r.o.